Date: June 22, 2021
Open Postdoc position at the Institute of Human Genetics, University of Heidelberg
We are looking for an enthusiastic postdoc to join our research group at the Institute of Human Genetics of the University of Heidelberg. The general interest of the lab is in the molecular mechanisms underlying hereditary kidney and metabolic diseases. Most of these diseases are caused by single-gene defects and thereby offer unique opportunities to decipher fundamental regulatory pathways of human development and physiology and to develop targeted diagnostic and therapeutic options. Recent publications include Jouandin, Marelja et al, Biorxiv 2020; Bedin et al, J Clin Invest 2020; Marchesin et al, Cell Rep 2019; Goncalves et al, PloS Genetics 2018; Simons, JASN 2018; Rujano et al, J Exp Med 2017; Trepiccione et al, JASN 2016; Gleixner et al, Cell Rep 2014. We combine human genetics with several experimental approaches, including fly and mouse genetics, cell culture, microscopy and biochemistry. See www.simons-lab.de for more info.
We offer an exciting ERC-funded translational project aimed at exploring the role of Wnt signaling in renal development and at solving the molecular cause of patients with renal hypodysplasia. For this project, we invite applications from individuals with a solid background in molecular cell biology. Prior experience with stem cells (e.g. mouse ESCs or human iPSCs), organoids, mice, live imaging and kidney research is an advantage but not a prerequisite. The project will be carried out in a stimulating work environment with scientific collaborations within the institute and across the Heidelberg life science community, in particular with the Aulehla group at EMBL.
The successful applicant will have good communication and organisational skills and a PhD in a relevant area (or be in the final stages of completion). We also invite applications from research-oriented MDs. Candidates are expected to be highly motivated and to work independently with a strong work ethic. As we are an international lab, proficiency in English language is a requirement. Applications including a cover letter, a detailed CV including a publication list and contacts of up to three referees should be sent as soon as possible to firstname.lastname@example.org
developmental biology, Wnt signaling, renal hypodysplasia, organoids, kidney, live imaging